Marked extension of proliferation of rat Sertoli cells in culture using recombinant human FSH
نویسندگان
چکیده
منابع مشابه
Signal transduction pathways in FSH regulation of rat Sertoli cell proliferation.
The final number of Sertoli cells reached during the proliferative periods determines sperm production capacity in adulthood. It is well known that FSH is the major Sertoli cell mitogen; however, little is known about the signal transduction pathways that regulate the proliferation of Sertoli cells. The hypothesis of this investigation was that FSH regulates proliferation through a PI3K/Akt/mTO...
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Testosterone and follicle-stimulating hormone (FSH) are required to obtain full reproductive potential. In the testis, somatic Sertoli cells transduce signals from testosterone and FSH into the production of factors that are required by germ cells as they mature into spermatozoa. Recent advances in identifying new signaling pathways that are regulated by FSH and testosterone have allowed for re...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2002
ISSN: 1470-1626,1741-7899
DOI: 10.1530/reprod/124.5.633